STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A316YY80Replication protein A, subunit RPA32. (269 aa)    
Predicted Functional Partners:
A0A316YFM0
3'-5' exonuclease domain-containing protein.
   
 0.999
A0A316YVX8
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
   
 0.999
A0A316YVE3
Replication factor A protein 3.
    
 0.998
A0A316YE68
DNA/RNA polymerase.
   
 
 0.981
A0A316YGW7
Uncharacterized protein.
    
 0.973
A0A316YWP1
Uncharacterized protein.
   
 0.970
A0A316YTU9
ATP-dependent DNA helicase.
   
 0.968
A0A316YMQ7
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.956
A0A316YXJ5
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.920
A0A316YHP8
DNA repair protein.
    
 0.916
Your Current Organism:
Acaromyces ingoldii
NCBI taxonomy Id: 215250
Other names: A. ingoldii, AS001, CBS 110050
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.