STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A316YYA5Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (654 aa)    
Predicted Functional Partners:
PRT1
Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.
  
 
0.937
A0A316YSV9
Serine/threonine-protein kinase.
   
 
 0.715
A0A316YIP3
Histidyl-tRNA synthetase.
   
 
 0.567
A0A316YR78
Putative SUI2-translation initiation factor eIF-2 alpha chain.
   
 
 0.554
A0A316YM93
Putative translation initiation factor eIF2 gamma chain.
   
 
 0.550
TIF32
Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
   
 
 0.521
A0A316YGD9
Tr-type G domain-containing protein.
   
  
 0.519
A0A316YGI9
Uncharacterized protein.
    
  0.491
A0A316YNJ6
Uncharacterized protein.
   
  0.488
A0A316Z1A1
RIO domain-containing protein.
   
   0.480
Your Current Organism:
Acaromyces ingoldii
NCBI taxonomy Id: 215250
Other names: A. ingoldii, AS001, CBS 110050
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.