STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
top2bDNA topoisomerase 2-beta. (1613 aa)    
Predicted Functional Partners:
smc2
Structural maintenance of chromosomes protein 2.
   
 
 0.887
smc4
Structural maintenance of chromosomes protein 4 isoform X1.
   
 
 0.828
ncaph
Condensin complex subunit 2.
   
 
 0.825
ube2c
Ubiquitin-conjugating enzyme E2 C.
   
 0.796
LOC104927484
DNA topoisomerase 1-like.
   
 
 0.784
LOC104920682
DNA topoisomerase I, mitochondrial isoform X1.
   
 
 0.784
LOC104939372
DNA topoisomerase 1.
   
 
 0.784
cdc20
Cell division cycle 20, cofactor of APC complex.
   
 
 0.782
LOC104918068
Baculoviral IAP repeat-containing protein 5.2.
   
  
 0.781
dlgap5
Disks large-associated protein 5 isoform X1.
   
  
 0.765
Your Current Organism:
Larimichthys crocea
NCBI taxonomy Id: 215358
Other names: L. crocea, Pseudosciaena amblyceps, Pseudosciaena crocea, Sciaena crocea, croceine croaker, large yellow croaker
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