kif26a protein (Larimichthys crocea) - STRING interaction network

Nodes:

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

kif26a

Kinesin-like protein KIF26A isoform X1. (2036 aa)

Predicted Functional Partners:

LOC104936066

0.741

LOC104933922

0.741

kif11

0.595

uchl5

0.580

bap1

0.580

ift80

0.526

KIF18A

0.512

zw10

0.485

IFT122

0.483

Cenpe

0.483

Your Current Organism:

Larimichthys crocea

NCBI taxonomy Id: 215358
Other names: L. crocea, Pseudosciaena amblyceps, Pseudosciaena crocea, Sciaena crocea, croceine croaker, large yellow croaker

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cenpe	KIF18A	ENSLCRP00005041692	ENSLCRP00005018612	Centromere-associated protein E.	Kinesin-like protein KIF18A isoform X1.	0.960
Cenpe	LOC104933922	ENSLCRP00005041692	ENSLCRP00005042290	Centromere-associated protein E.	Kinesin-associated protein 3 isoform X1.	0.566
Cenpe	LOC104936066	ENSLCRP00005041692	ENSLCRP00005014010	Centromere-associated protein E.	Kinesin-associated protein 3.	0.566
Cenpe	ift80	ENSLCRP00005041692	ENSLCRP00005022357	Centromere-associated protein E.	Intraflagellar transport protein 80 homolog.	0.441
Cenpe	kif11	ENSLCRP00005041692	ENSLCRP00005050466	Centromere-associated protein E.	Kinesin-like protein KIF11 isoform X1.	0.981
Cenpe	kif26a	ENSLCRP00005041692	ENSLCRP00005039338	Centromere-associated protein E.	Kinesin-like protein KIF26A isoform X1.	0.483
Cenpe	zw10	ENSLCRP00005041692	ENSLCRP00005042389	Centromere-associated protein E.	Centromere/kinetochore protein zw10 homolog.	0.731
IFT122	LOC104933922	ENSLCRP00005014192	ENSLCRP00005042290	Intraflagellar transport protein 122 homolog isoform X1.	Kinesin-associated protein 3 isoform X1.	0.606
IFT122	LOC104936066	ENSLCRP00005014192	ENSLCRP00005014010	Intraflagellar transport protein 122 homolog isoform X1.	Kinesin-associated protein 3.	0.606
IFT122	ift80	ENSLCRP00005014192	ENSLCRP00005022357	Intraflagellar transport protein 122 homolog isoform X1.	Intraflagellar transport protein 80 homolog.	0.873
IFT122	kif26a	ENSLCRP00005014192	ENSLCRP00005039338	Intraflagellar transport protein 122 homolog isoform X1.	Kinesin-like protein KIF26A isoform X1.	0.483
KIF18A	Cenpe	ENSLCRP00005018612	ENSLCRP00005041692	Kinesin-like protein KIF18A isoform X1.	Centromere-associated protein E.	0.960
KIF18A	LOC104933922	ENSLCRP00005018612	ENSLCRP00005042290	Kinesin-like protein KIF18A isoform X1.	Kinesin-associated protein 3 isoform X1.	0.596
KIF18A	LOC104936066	ENSLCRP00005018612	ENSLCRP00005014010	Kinesin-like protein KIF18A isoform X1.	Kinesin-associated protein 3.	0.596
KIF18A	kif11	ENSLCRP00005018612	ENSLCRP00005050466	Kinesin-like protein KIF18A isoform X1.	Kinesin-like protein KIF11 isoform X1.	0.978
KIF18A	kif26a	ENSLCRP00005018612	ENSLCRP00005039338	Kinesin-like protein KIF18A isoform X1.	Kinesin-like protein KIF26A isoform X1.	0.512
KIF18A	zw10	ENSLCRP00005018612	ENSLCRP00005042389	Kinesin-like protein KIF18A isoform X1.	Centromere/kinetochore protein zw10 homolog.	0.483
LOC104933922	Cenpe	ENSLCRP00005042290	ENSLCRP00005041692	Kinesin-associated protein 3 isoform X1.	Centromere-associated protein E.	0.566
LOC104933922	IFT122	ENSLCRP00005042290	ENSLCRP00005014192	Kinesin-associated protein 3 isoform X1.	Intraflagellar transport protein 122 homolog isoform X1.	0.606
LOC104933922	KIF18A	ENSLCRP00005042290	ENSLCRP00005018612	Kinesin-associated protein 3 isoform X1.	Kinesin-like protein KIF18A isoform X1.	0.596

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.875

expected number of edges:

11

PPI enrichment p-value:

4.94e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009252

Peptidoglycan biosynthetic process

8 of 38

1.96

4.42

8.65e-12

GO:0071555

Cell wall organization

4 of 26

1.83

2.07

2.98e-05

GO:0008360

Regulation of cell shape

4 of 26

1.83

2.07

2.98e-05

GO:0051301

Cell division

3 of 44

1.47

0.99

0.0063

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008955

Peptidoglycan glycosyltransferase activity

5 of 7

2.49

4.05

1.40e-08

GO:0008658

Penicillin binding

4 of 6

2.46

3.21

7.03e-07

GO:0009002

Serine-type D-Ala-D-Ala carboxypeptidase activity

3 of 5

2.42

2.34

3.71e-05

GO:0016757

Glycosyltransferase activity

6 of 61

1.63

2.33

7.03e-07

GO:0004180

Carboxypeptidase activity

4 of 19

1.96

2.32

1.32e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1359

Mixed, incl. Peptidoglycan biosynthesis, and Cell division

11 of 46

2.02

6.54

2.68e-19

CL:1363

Mixed, incl. Peptidoglycan biosynthesis, and Cell division site

9 of 33

2.07

5.85

1.83e-15

CL:1416

Peptidoglycan glycosyltransferase activity, and Peptidoglycan muralytic activity

4 of 5

2.54

3.48

2.33e-07

CL:1365

Mixed, incl. Cell shape, and Cell division site

5 of 23

1.98

3.01

2.35e-07

CL:1398

Mixed, incl. Cell cycle protein, and Cell morphogenesis

2 of 5

2.24

1.07

0.0102

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00550

Peptidoglycan biosynthesis

6 of 33

1.9

3.33

1.15e-08

map01501

beta-Lactam resistance

4 of 121

1.16

0.79

0.0083

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0032153

Cell division site

3 of 9

2.16

1.68

0.00059

GOCC:0005618

Cell wall

3 of 21

1.79

1.26

0.0027

GOCC:0071944

Cell periphery

7 of 713

0.63

0.39

0.0319

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0961

Cell wall biogenesis/degradation

3 of 16

1.91

1.38

0.0018

KW-0133

Cell shape

3 of 16

1.91

1.38

0.0018

KW-0997

Cell inner membrane

3 of 42

1.49

0.94

0.0087

KW-0573

Peptidoglycan synthesis

2 of 15

1.76

0.87

0.0198

KW-0328

Glycosyltransferase

2 of 22

1.6

0.73

0.0348

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00905

Penicillin binding protein transpeptidase domain

4 of 6

2.46

2.98

2.11e-06

PF03717

Penicillin-binding Protein dimerisation domain

2 of 2

2.64

1.11

0.0097

PF01098

Cell cycle protein

2 of 2

2.64

1.11

0.0097

PF00912

Transglycosylase

2 of 4

2.34

1.04

0.0120

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001460

Penicillin-binding protein, transpeptidase

4 of 6

2.46

2.92

2.73e-06

IPR012338

Beta-lactamase/transpeptidase-like

5 of 18

2.08

2.84

1.26e-06

IPR036138

Penicillin-binding protein, dimerisation domain superfamily

2 of 2

2.64

0.98

0.0167

IPR005311

Penicillin-binding protein, dimerisation domain

2 of 2

2.64

0.98

0.0167

IPR001182

Probable peptidoglycan glycosyltransferase FtsW/RodA

2 of 2

2.64

0.98

0.0167

(more ...)

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