node1 | node2 | node1 annotation | node2 annotation | score |
A0A4P9ZK47 | A0A4P9ZKD5 | P-loop containing nucleoside triphosphate hydrolase protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.710 |
A0A4P9ZK47 | A0A4P9ZNQ7 | P-loop containing nucleoside triphosphate hydrolase protein. | SPOC like C-terminal domain-containing protein. | 0.684 |
A0A4P9ZK47 | A0A4P9ZQX5 | P-loop containing nucleoside triphosphate hydrolase protein. | Tyrosyl-DNA phosphodiesterase-domain-containing protein. | 0.775 |
A0A4P9ZK47 | A0A4P9ZUX0 | P-loop containing nucleoside triphosphate hydrolase protein. | ERCC4 domain-containing protein. | 0.999 |
A0A4P9ZK47 | A0A4P9ZXY4 | P-loop containing nucleoside triphosphate hydrolase protein. | SPOC like C-terminal domain-containing protein. | 0.579 |
A0A4P9ZK47 | A0A4P9ZZ22 | P-loop containing nucleoside triphosphate hydrolase protein. | Uncharacterized protein. | 0.504 |
A0A4P9ZK47 | A0A4P9ZZ46 | P-loop containing nucleoside triphosphate hydrolase protein. | ERCC4 domain-containing protein. | 0.872 |
A0A4P9ZK47 | A0A4Q0A1J6 | P-loop containing nucleoside triphosphate hydrolase protein. | DNA ligase. | 0.671 |
A0A4P9ZK47 | A0A4V1J3Y8 | P-loop containing nucleoside triphosphate hydrolase protein. | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. | 0.812 |
A0A4P9ZKD5 | A0A4P9ZK47 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | P-loop containing nucleoside triphosphate hydrolase protein. | 0.710 |
A0A4P9ZKD5 | A0A4P9ZNQ7 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | SPOC like C-terminal domain-containing protein. | 0.610 |
A0A4P9ZKD5 | A0A4P9ZQX5 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Tyrosyl-DNA phosphodiesterase-domain-containing protein. | 0.917 |
A0A4P9ZKD5 | A0A4P9ZUX0 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | ERCC4 domain-containing protein. | 0.782 |
A0A4P9ZKD5 | A0A4P9ZVB3 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | WLM domain-containing protein. | 0.644 |
A0A4P9ZKD5 | A0A4P9ZXY4 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | SPOC like C-terminal domain-containing protein. | 0.557 |
A0A4P9ZKD5 | A0A4P9ZZ22 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Uncharacterized protein. | 0.591 |
A0A4P9ZKD5 | A0A4P9ZZ46 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | ERCC4 domain-containing protein. | 0.626 |
A0A4P9ZKD5 | A0A4Q0A1J6 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | DNA ligase. | 0.544 |
A0A4P9ZKD5 | A0A4V1J3Y8 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. | 0.501 |
A0A4P9ZNQ7 | A0A4P9ZK47 | SPOC like C-terminal domain-containing protein. | P-loop containing nucleoside triphosphate hydrolase protein. | 0.684 |