STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A4P9ZQX5Tyrosyl-DNA phosphodiesterase-domain-containing protein. (579 aa)    
Predicted Functional Partners:
A0A4P9ZKD5
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
    
 
 0.917
A0A4P9ZZ22
Uncharacterized protein.
    
 
 0.826
A0A4Q0A1J6
DNA ligase.
   
 
 0.818
A0A4P9ZNQ7
SPOC like C-terminal domain-containing protein.
     
 0.810
A0A4P9ZXY4
SPOC like C-terminal domain-containing protein.
    
 0.798
A0A4P9ZVB3
WLM domain-containing protein.
    
 
 0.787
A0A4P9ZK47
P-loop containing nucleoside triphosphate hydrolase protein.
   
 
 0.775
A0A4P9ZUX0
ERCC4 domain-containing protein.
   
 
 0.757
A0A4V1J3Y8
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
   
 
 0.726
A0A4P9ZZ46
ERCC4 domain-containing protein.
   
 
 0.715
Your Current Organism:
Dimargaris cristalligena
NCBI taxonomy Id: 215637
Other names: D. cristalligena
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