node1 | node2 | node1 annotation | node2 annotation | score |
A0A4P9ZIX2 | A0A4P9ZNI4 | dUTPase-like protein. | Thymidylate kinase-domain-containing protein. | 0.533 |
A0A4P9ZIX2 | A0A4P9ZWV6 | dUTPase-like protein. | Temperature dependent protein affecting M2 dsRNA replication-domain-containing protein. | 0.533 |
A0A4P9ZIX2 | A0A4V1J5N3 | dUTPase-like protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.583 |
A0A4P9ZNI4 | A0A4P9ZIX2 | Thymidylate kinase-domain-containing protein. | dUTPase-like protein. | 0.533 |
A0A4P9ZNI4 | A0A4P9ZWV6 | Thymidylate kinase-domain-containing protein. | Temperature dependent protein affecting M2 dsRNA replication-domain-containing protein. | 0.747 |
A0A4P9ZNI4 | A0A4V1J5N3 | Thymidylate kinase-domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.589 |
A0A4P9ZSA5 | A0A4P9ZUM6 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.806 |
A0A4P9ZSA5 | A0A4P9ZWV6 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Temperature dependent protein affecting M2 dsRNA replication-domain-containing protein. | 0.737 |
A0A4P9ZSA5 | A0A4Q0A1C7 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.818 |
A0A4P9ZSA5 | A0A4Q0A1V1 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.833 |
A0A4P9ZSA5 | A0A4Q0A308 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Dihydrolipoyl dehydrogenase. | 0.816 |
A0A4P9ZUM6 | A0A4P9ZSA5 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.806 |
A0A4P9ZUM6 | A0A4P9ZWV6 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Temperature dependent protein affecting M2 dsRNA replication-domain-containing protein. | 0.636 |
A0A4P9ZUM6 | A0A4Q0A1C7 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.812 |
A0A4P9ZUM6 | A0A4Q0A1V1 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.835 |
A0A4P9ZUM6 | A0A4Q0A1Y5 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Protein disulfide-isomerase tigA; Belongs to the protein disulfide isomerase family. | 0.824 |
A0A4P9ZV08 | A0A4P9ZWV6 | LsmAD domain-containing protein. | Temperature dependent protein affecting M2 dsRNA replication-domain-containing protein. | 0.730 |
A0A4P9ZWV6 | A0A4P9ZIX2 | Temperature dependent protein affecting M2 dsRNA replication-domain-containing protein. | dUTPase-like protein. | 0.533 |
A0A4P9ZWV6 | A0A4P9ZNI4 | Temperature dependent protein affecting M2 dsRNA replication-domain-containing protein. | Thymidylate kinase-domain-containing protein. | 0.747 |
A0A4P9ZWV6 | A0A4P9ZSA5 | Temperature dependent protein affecting M2 dsRNA replication-domain-containing protein. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.737 |