STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A4Q0A1C5GTP cyclohydrolase II-domain-containing protein. (410 aa)    
Predicted Functional Partners:
A0A4P9ZVP9
Riboflavin synthase alpha chain.
 0.997
A0A4Q0A202
Dihydrofolate reductase-like domain-containing protein.
  
 0.988
A0A4P9ZZJ5
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 
 0.979
A0A4P9ZY58
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
 
   
 0.969
A0A4P9ZTA7
GTP_cyclohydroI domain-containing protein.
   
 
 0.829
A0A4Q0A1G5
Nucleoside diphosphate kinase.
  
 0.823
A0A4Q0A2L1
Cytidine deaminase-like protein.
 
  
 0.810
A0A4V1J5N3
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
     
 0.802
A0A4P9ZYU9
Nucleoside diphosphate kinase.
  
 0.785
A0A4P9ZJJ9
PH domain-containing protein.
  
 0.777
Your Current Organism:
Dimargaris cristalligena
NCBI taxonomy Id: 215637
Other names: D. cristalligena
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