STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pqqCPyrroloquinoline-quinone synthase; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. (249 aa)    
Predicted Functional Partners:
pqqB
Coenzyme PQQ synthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
  
 0.998
mftC
Putative mycofactocin radical SAM maturase MftC; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
 
  
 0.984
pqqD
Coenzyme PQQ synthesis protein D; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
 
  
 0.976
moxF
Methanol dehydrogenase [cytochrome c] subunit 1; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
 
  
 0.849
ARE82956.1
Hypothetical protein; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
 
     0.735
ARE82955.1
Sulfur oxidation protein SoxY; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
 
     0.718
ARE82957.1
Hypothetical protein; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
 
     0.709
ARE82934.1
Antigen Lp49; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg; orfC.
  
     0.697
ARE82935.1
Periplasmic binding protein; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
  
     0.685
pqqA
Coenzyme PQQ synthesis protein PqqA; Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide; Belongs to the PqqA family.
       0.668
Your Current Organism:
Roseovarius mucosus
NCBI taxonomy Id: 215743
Other names: DSM 17069, NCIMB 14077, R. mucosus, Roseobacter sp. 253-13, Roseovarius mucosus Biebl et al. 2005, Roseovarius sp. DFL-24, strain DFL-24
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.