STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdhASuccinate dehydrogenase flavoprotein subunit; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (600 aa)    
Predicted Functional Partners:
frdB
Fumarate reductase iron-sulfur subunit; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.999
sdhC-2
Succinate dehydrogenase cytochrome b556 subunit; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
 
 0.999
ARE83809.1
Succinate dehydrogenase/fumarate reductase transmembrane subunit; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
  
 0.999
sdhB
Succinate dehydrogenase iron-sulfur subunit; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.999
sdhC
Succinate dehydrogenase 2 membrane subunit SdhC; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
  
 0.998
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 0.996
ARE83521.1
Succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
  
 0.995
sucD
succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.977
sucD-2
succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.977
sucC
succinate--CoA ligase [ADP-forming] subunit beta; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
  
 0.976
Your Current Organism:
Roseovarius mucosus
NCBI taxonomy Id: 215743
Other names: DSM 17069, NCIMB 14077, R. mucosus, Roseobacter sp. 253-13, Roseovarius mucosus Biebl et al. 2005, Roseovarius sp. DFL-24, strain DFL-24
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