STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabI-2Enoyl-[acyl-carrier-protein] reductase [NADH] FabI; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg. (268 aa)    
Predicted Functional Partners:
fabD
Malonyl CoA-acyl carrier protein transacylase; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
 
 
 0.992
fabB
3-oxoacyl-[acyl-carrier-protein] synthase 1; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.987
fabF
3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.980
fabZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.971
fabA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
  
 
 0.962
fabG
3-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
0.921
ppsA
Phthiocerol synthesis polyketide synthase type I PpsA; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
  
  
 0.920
tsaC1
4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
  
 
 0.915
fabI
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
  
  
 
0.903
fabG-6
3-oxoacyl-[acyl-carrier-protein] reductase FabG; Bacteria and source DNA available from Adrian K. Clarke, Department of Biological and Environmental Sciences, University of Gothenburg.
   
 
 0.903
Your Current Organism:
Roseovarius mucosus
NCBI taxonomy Id: 215743
Other names: DSM 17069, NCIMB 14077, R. mucosus, Roseobacter sp. 253-13, Roseovarius mucosus Biebl et al. 2005, Roseovarius sp. DFL-24, strain DFL-24
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.