STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trpE_2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (593 aa)    
Predicted Functional Partners:
trpD
Glutamine amidotransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 0.999
pabA
Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.970
KGL12875.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.965
pheA
Chloride transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.924
aroE
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.893
ilvE_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.868
mqnA
Menaquinone biosynthesis protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
     
  0.821
folP
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.710
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
    
 0.689
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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