STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icfACarbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)    
Predicted Functional Partners:
yrdA
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.845
KGL12279.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.845
cah_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.834
KGL13490.1
Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.775
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.707
dedA
Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.649
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.565
KGL13038.1
Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.565
fliM2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.564
fliN
One of three proteins involved in switching the direction of the flagellar rotation; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.435
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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