STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dedAAlkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)    
Predicted Functional Partners:
icfA
Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.649
fliN
One of three proteins involved in switching the direction of the flagellar rotation; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.588
fliW2
Flagellar assembly protein FliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
   
    0.575
KGL12674.1
Flagellar assembly protein FliW; Binds to flagellin and appears to stabilize flagellin during flagella assembly; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.575
csrA
Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
   
    0.526
macB_1
Multidrug ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.503
fliG
Flagellar motor switch protein FliG; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.451
flgC
Flagellar basal body rod protein FlgC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flagella basal body rod proteins family.
   
   0.433
KGL12460.1
Flagellar basal body rod protein FlgC; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.433
adhB
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.416
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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