Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nikRNickel responsive regulator; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (142 aa)    
Predicted Functional Partners:
KGL13175.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.661
arsC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family.
       0.612
tolQ_3
Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.486
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
     
 0.454
KGL13173.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.445
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.441
nikA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.426
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.