Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
comMFis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (516 aa)    
Predicted Functional Partners:
KGL12370.1
DNA processing protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.795
flgG_1
Flagellar basal body rod protein FlgG; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.722
ruvC
Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
   
 0.622
KGL13855.1
Transformation system protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.551
KGL14028.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0102 family.
 
  
 0.511
secD
Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
     0.481
KGL12976.1
Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.420
comEA
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.409
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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