Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cysQHypothetical protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (297 aa)    
Predicted Functional Partners:
KGL14004.1
Adenylylsulfate kinase; Converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.897
KGL13426.1
Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.868
frdA
Part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.620
oorD
2-oxoglutarate:acceptor oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.611
KGL13282.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.512
KGL13280.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.412
cysK_2
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.409
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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