STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icdIsocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (737 aa)    
Predicted Functional Partners:
oorD
2-oxoglutarate:acceptor oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.981
oorA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.975
oorC
2-oxoglutarate:acceptor oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.975
oorB
2-oxoglutarate ferredoxin oxidoreductase subunit beta; Catalyzes the coenzyme A-dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.956
KGL13830.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.921
acnB
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family.
  
 
 0.919
gdh
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.863
KGL13185.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.853
KGL13112.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
  0.835
purB_2
Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
  0.812
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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