Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
KGL12833.1Hemerythrin-like metal-binding domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)    
Predicted Functional Partners:
rpoBC
DNA-directed RNA polymerase subunit beta/beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.940
KGL12705.1
DNA-directed RNA polymerase subunit beta/beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; fusion of rpoB and rpoC; beta and beta' subunits are part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.940
cheA
Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.916
cheV_2
Chemotaxis protein CheV; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.912
cheV_1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.912
KGL13830.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.908
phoB_1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.885
ompR
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.885
cusR
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.885
phoB_2
ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.885
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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