STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemN_1Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (455 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.964
hemJ
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.884
hemZ
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
0.850
yccM
4Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.841
ccoN
Cbb3-type cytochrome c oxidase subunit I; CcoN; FixN; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heme-copper respiratory oxidase family.
 
  
 0.820
KGL12725.1
Cbb3-type cytochrome c oxidase subunit I; CcoN; FixN; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.820
KGL12833.1
Hemerythrin-like metal-binding domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.810
ccoO
Peptidase S13; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.791
KGL12724.1
Peptidase S13; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.791
glpC
Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.735
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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