Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
oorD2-oxoglutarate:acceptor oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)    
Predicted Functional Partners:
oorC
2-oxoglutarate:acceptor oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
oorA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.995
oorB
2-oxoglutarate ferredoxin oxidoreductase subunit beta; Catalyzes the coenzyme A-dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.992
icd
Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family.
  
 
 0.980
sucD
succinate--CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.947
gltD_1
Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.946
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.934
gltD_2
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.896
KGL13830.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.887
porA
2-ketoisovalerate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.874
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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