STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGL12609.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (680 aa)    
Predicted Functional Partners:
hypE
Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.928
hyaD
Protein hydD; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.791
hydC
Ni/Fe hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.710
hyaB
Hydrogenase 2 large subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.690
KGL12613.1
Ni/Fe hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.679
hypC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.619
hypD
Hydrogenase formation protein HypD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family.
  
  
 0.609
ruvC
Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.593
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
     
 0.477
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
     
 0.443
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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