Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KGL12616.1Restriction endonuclease subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)    
Predicted Functional Partners:
KGL12222.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.944
hsdM
Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.933
KGL13252.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.931
KGL14009.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.928
KGL12583.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.909
hsdR1b
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.799
KGL13422.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.781
KGL13421.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.770
KGL12804.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.639
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
   0.548
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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