STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepDAminoacyl-histidine dipeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.939
pepA
Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.863
KGL13185.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.843
cysK_2
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.838
metB_2
Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.824
patB
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.802
KGL12617.1
Phospholipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.800
ggt
Gamma-glutamyltranspeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.765
KGL12225.1
Gamma-glutamyltranspeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.765
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
    
 0.743
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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