Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
palHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)    
Predicted Functional Partners:
tolB
tol-Pal system beta propeller repeat protein TolB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.978
lolC
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.878
guaA_2
Hypothetical protein; Catalyzes the synthesis of GMP from XMP.
  
 
  0.844
exbD3
Biopolymer transporter ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.815
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.814
KGL13038.1
Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.814
degP
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S1C family.
  
 
 
 0.803
fliF
Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
   
 
 0.779
tolQ_1
Flagellar motor protein MotA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.776
flgC
Flagellar basal body rod protein FlgC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flagella basal body rod proteins family.
   
   0.756
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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