STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mqnDsuccinate--CoA ligase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (288 aa)    
Predicted Functional Partners:
mqnC
Hypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
  
 0.968
mqnA
Menaquinone biosynthesis protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
  
 0.905
mqnE
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.895
KGL13254.1
Prenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiA prenyltransferase family.
 
     0.793
yigC
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiD family.
  
     0.642
fabG_3
3-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
   0.634
KGL13865.1
Purine nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.632
KGL12742.1
Purine nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.632
KGL12564.1
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.550
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
 
     0.482
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
Server load: low (26%) [HD]