Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acsA1acetyl-CoA synthetase AcsA1. (635 aa)    
Predicted Functional Partners:
acs
ADP-dependent acetyl-CoA synthetase Acs.
    
 0.969
BRM9_1452
acetyl-CoA acetyltransferase.
  
 
 0.964
cdhE
CO dehydrogenase/acetyl-CoA synthase gamma subunit CdhE; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
   
 
 0.946
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha KorA.
  
 
 0.927
acsA4
acetyl-CoA synthetase AcsA4.
  
  
0.920
porA
Pyruvate ferredoxin oxidoreductase alpha subunit PorA.
  
 
 0.918
porB
Pyruvate ferredoxin oxidoreductase beta subunit PorB.
  
 
 0.918
leuA
2-isopropylmalate synthase LeuA; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.917
aksA
Homocitrate synthase AksA; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.917
BRM9_2122
2-oxoacid ferredoxin oxidoreductase alpha subunit.
  
 
 0.915
Your Current Organism:
Methanobacterium formicicum
NCBI taxonomy Id: 2162
Other names: ATCC 33274, JCM 10132, M. formicicum, Methanobacterium sp. BRM9, NBRC 100475, OCM 55, strain MF
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