STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysKCysteine synthase CysKM. (328 aa)    
Predicted Functional Partners:
cysE
Serine O-acetyltransferase CysE.
 
 0.999
metC
Cystathionine gamma-synthase.
 
 0.998
cysD
O-acetylhomoserine/O-acetylserine sulfhydrylase MetZ/CysK2.
  
 
 0.983
ahcY
S-adenosyl-L-homocysteine hydrolase AhcY; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family.
  
 0.981
metE
Methionine synthase MetE.
  
 
 0.975
coaBC
Coenzyme A biosynthesis bifunctional protein CoaBC.
    
 0.972
BRM9_0473
Aminotransferase.
  
 
 0.968
BRM9_1523
CBS domain-containing protein.
 
  
  0.963
BRM9_1524
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
  
  
  0.962
cysS
cysteinyl-tRNA synthetase CysS; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.959
Your Current Organism:
Methanobacterium formicicum
NCBI taxonomy Id: 2162
Other names: ATCC 33274, JCM 10132, M. formicicum, Methanobacterium sp. BRM9, NBRC 100475, OCM 55, strain MF
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