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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
serBPhosphoserine phosphatase SerB. (496 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family.
    
  0.940
trpB2
Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.900
trpB
Tryptophan synthase beta subunit TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.900
trpA
Tryptophan synthase alpha subunit TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.900
tbp
TATA-box binding protein Tbp; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
       0.895
cysE
Serine O-acetyltransferase CysE.
     
 0.812
metX1
Homoserine O-acetyltransferase MetX1; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
     
  0.800
metX2
Homoserine O-acetyltransferase MetX2.
     
  0.800
acs
ADP-dependent acetyl-CoA synthetase Acs.
       0.697
BRM9_0691
Aminotransferase class V family.
     
  0.500
Your Current Organism:
Methanobacterium formicicum
NCBI taxonomy Id: 2162
Other names: ATCC 33274, JCM 10132, M. formicicum, Methanobacterium sp. BRM9, NBRC 100475, OCM 55, strain MF
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