node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAP86389.1 | EAP86588.1 | CA2559_10153 | CA2559_11148 | Hypothetical protein. | ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.693 |
EAP86389.1 | clpB | CA2559_10153 | CA2559_09888 | Hypothetical protein. | Putative heat shock ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.693 |
EAP86389.1 | dnaK | CA2559_10153 | CA2559_07165 | Hypothetical protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.878 |
EAP86389.1 | groL | CA2559_10153 | CA2559_00670 | Hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.666 |
EAP86389.1 | groS | CA2559_10153 | CA2559_00675 | Hypothetical protein. | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.576 |
EAP86389.1 | grpE | CA2559_10153 | CA2559_08251 | Hypothetical protein. | GrpE protein (Hsp-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.764 |
EAP86389.1 | lon | CA2559_10153 | CA2559_09893 | Hypothetical protein. | ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.574 |
EAP86588.1 | EAP86389.1 | CA2559_11148 | CA2559_10153 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Hypothetical protein. | 0.693 |
EAP86588.1 | EAP87456.1 | CA2559_11148 | CA2559_01835 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Hypothetical protein. | 0.695 |
EAP86588.1 | EAP87833.1 | CA2559_11148 | CA2559_03720 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | DnaJ domain containing protein. | 0.698 |
EAP86588.1 | dnaJ | CA2559_11148 | CA2559_08256 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.693 |
EAP86588.1 | dnaK | CA2559_11148 | CA2559_07165 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.880 |
EAP86588.1 | groL | CA2559_11148 | CA2559_00670 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.647 |
EAP86588.1 | groS | CA2559_11148 | CA2559_00675 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.645 |
EAP86588.1 | grpE | CA2559_11148 | CA2559_08251 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | GrpE protein (Hsp-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.746 |
EAP86588.1 | lon | CA2559_11148 | CA2559_09893 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.647 |
EAP87456.1 | EAP86588.1 | CA2559_01835 | CA2559_11148 | Hypothetical protein. | ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.695 |
EAP87456.1 | clpB | CA2559_01835 | CA2559_09888 | Hypothetical protein. | Putative heat shock ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.693 |
EAP87456.1 | dnaK | CA2559_01835 | CA2559_07165 | Hypothetical protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.878 |
EAP87456.1 | groL | CA2559_01835 | CA2559_00670 | Hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.666 |