EAP86025.1 protein (Croceibacter atlanticus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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[Homology]

Score

EAP86025.1

Hypothetical protein. (293 aa)

Predicted Functional Partners:

EAP88000.1

0.752

EAP87427.1

0.717

EAP88294.1

0.645

EAP87778.1

0.613

EAP86472.1

0.596

EAP87686.1

0.593

EAP87378.1

0.591

EAP85984.1

0.589

EAP86301.1

0.571

EAP86598.1

0.571

Your Current Organism:

Croceibacter atlanticus

NCBI taxonomy Id: 216432
Other names: C. atlanticus HTCC2559, Croceibacter atlanticus HTCC2559, Croceibacter atlanticus str. HTCC2559, Croceibacter atlanticus strain HTCC2559

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EAP85984.1	EAP86025.1	CA2559_08126	CA2559_08331	Hypothetical protein.	Hypothetical protein.	0.589
EAP85984.1	EAP86301.1	CA2559_08126	CA2559_09713	Hypothetical protein.	Hypothetical protein.	0.726
EAP85984.1	EAP86598.1	CA2559_08126	CA2559_11198	Hypothetical protein.	Hypothetical protein.	0.532
EAP85984.1	EAP87378.1	CA2559_08126	CA2559_01445	Hypothetical protein.	Putative esterase.	0.770
EAP85984.1	EAP87686.1	CA2559_08126	CA2559_02985	Hypothetical protein.	Hypothetical protein.	0.755
EAP85984.1	EAP88294.1	CA2559_08126	CA2559_06025	Hypothetical protein.	Lipoprotein, putative.	0.545
EAP86025.1	EAP85984.1	CA2559_08331	CA2559_08126	Hypothetical protein.	Hypothetical protein.	0.589
EAP86025.1	EAP86301.1	CA2559_08331	CA2559_09713	Hypothetical protein.	Hypothetical protein.	0.571
EAP86025.1	EAP86472.1	CA2559_08331	CA2559_10568	Hypothetical protein.	Hypothetical protein.	0.596
EAP86025.1	EAP86598.1	CA2559_08331	CA2559_11198	Hypothetical protein.	Hypothetical protein.	0.571
EAP86025.1	EAP87378.1	CA2559_08331	CA2559_01445	Hypothetical protein.	Putative esterase.	0.591
EAP86025.1	EAP87427.1	CA2559_08331	CA2559_01690	Hypothetical protein.	Hypothetical protein.	0.717
EAP86025.1	EAP87686.1	CA2559_08331	CA2559_02985	Hypothetical protein.	Hypothetical protein.	0.593
EAP86025.1	EAP87778.1	CA2559_08331	CA2559_03445	Hypothetical protein.	Hypothetical protein.	0.613
EAP86025.1	EAP88000.1	CA2559_08331	CA2559_04555	Hypothetical protein.	Hypothetical protein.	0.752
EAP86025.1	EAP88294.1	CA2559_08331	CA2559_06025	Hypothetical protein.	Lipoprotein, putative.	0.645
EAP86301.1	EAP85984.1	CA2559_09713	CA2559_08126	Hypothetical protein.	Hypothetical protein.	0.726
EAP86301.1	EAP86025.1	CA2559_09713	CA2559_08331	Hypothetical protein.	Hypothetical protein.	0.571
EAP86301.1	EAP87378.1	CA2559_09713	CA2559_01445	Hypothetical protein.	Putative esterase.	0.570
EAP86301.1	EAP87686.1	CA2559_09713	CA2559_02985	Hypothetical protein.	Hypothetical protein.	0.518

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

23

average node degree:

4.18

avg. local clustering coefficient:

0.875

expected number of edges:

11

PPI enrichment p-value:

0.000953

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000226

Microtubule cytoskeleton organization

9 of 481

1.57

2.85

5.54e-10

GO:0007051

Spindle organization

5 of 119

1.92

2.55

2.78e-06

GO:0022402

Cell cycle process

9 of 629

1.45

2.4

3.00e-09

GO:0021987

Cerebral cortex development

4 of 57

2.15

2.38

1.79e-05

GO:0007098

Centrosome cycle

4 of 60

2.12

2.36

1.93e-05

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005815

Microtubule organizing center

8 of 610

1.42

2.1

7.36e-08

GO:0000922

Spindle pole

4 of 126

1.8

1.86

9.51e-05

GO:0005813

Centrosome

6 of 409

1.47

1.82

7.21e-06

GO:0005856

Cytoskeleton

9 of 1957

0.96

1.01

7.21e-06

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:12250

Mixed, incl. Alpha-N-methyltransferase NTM1, and Short myomegalin-like EB1 binding protein, N-terminal

3 of 7

2.93

2.51

2.61e-05

CL:12022

Mixed, incl. Anchoring of the basal body to the plasma membrane, and Gamma-tubulin complex

5 of 121

1.92

2.29

1.26e-05

CL:17111

Microtubule plus-end binding, and Mitotic cell cycle, embryonic

2 of 18

2.35

0.75

0.0420

CL:12029

Procentriole replication complex, and Loss of Nlp from mitotic centrosomes

2 of 18

2.35

0.75

0.0420

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

kmr04068

FoxO signaling pathway

3 of 156

1.58

0.96

0.0098

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00659

POLO box duplicated region

3 of 4

3.17

2.83

7.46e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR039915

TACC family

3 of 4

3.17

2.56

2.34e-05

IPR007707

Transforming acidic coiled-coil-containing protein, C-terminal

3 of 4

3.17

2.56

2.34e-05

IPR000959

POLO box domain

3 of 4

3.17

2.56

2.34e-05

IPR036947

POLO box domain superfamily

2 of 3

3.12

1.32

0.0041

IPR033701

First polo-box domain

2 of 3

3.12

1.32

0.0041

(more ...)

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