Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KJW13967.13-methyladenine DNA glycosylase; Constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)    
Predicted Functional Partners:
KJW13959.1
Methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.907
KJW13965.1
DNA repair ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
sbcD
Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
       0.773
argR-2
ArgR family transcriptional regulator; Regulates arginine biosynthesis genes.
  
    0.492
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
      0.481
KJW13968.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.479
KJW13964.1
Penicillin acylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.470
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.425
Your Current Organism:
Lactobacillus spicheri
NCBI taxonomy Id: 216463
Other names: DSM 15429, JCM 15956, L. spicheri, LMG 21871, LMG:21871, LTH 5753, Lactobacillus spicheri Meroth et al. 2004
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