Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KJW13757.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (132 aa)    
Predicted Functional Partners:
KJW12056.1
Dithiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.826
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.759
KJW12212.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.698
recU
Holliday junction endonuclease; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
     0.655
KJW11954.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0473 family.
 
     0.603
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
    0.483
KJW13529.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.462
KJW13150.1
Cell surface protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.454
KJW12008.1
DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.442
KJW12298.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.417
Your Current Organism:
Lactobacillus spicheri
NCBI taxonomy Id: 216463
Other names: DSM 15429, JCM 15956, L. spicheri, LMG 21871, LMG:21871, LTH 5753, Lactobacillus spicheri Meroth et al. 2004
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