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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KJW13185.12-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)    
Predicted Functional Partners:
KJW13183.1
Sugar phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
KJW13477.1
Ribulose-phosphate 3-epimerase; Catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.978
KJW12391.1
Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.951
KJW13187.1
6-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.932
KJW13186.1
3-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.918
KJW13184.1
Gluconate:proton symporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.886
KJW11879.1
2-deoxy-D-gluconate 3-dehydrogenase; Involved in the metabolism of 2-deoxyglucose; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.868
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.848
KJW13188.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.844
KJW13462.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.837
Your Current Organism:
Lactobacillus spicheri
NCBI taxonomy Id: 216463
Other names: DSM 15429, JCM 15956, L. spicheri, LMG 21871, LMG:21871, LTH 5753, Lactobacillus spicheri Meroth et al. 2004
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