Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KJW12033.1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (626 aa)    
Predicted Functional Partners:
KJW12035.1
Aspartate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.984
asnA
Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.931
KJW12916.1
Asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.916
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.907
KJW13410.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.858
KJW12820.1
Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family.
     
 0.836
KJW12034.1
Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.780
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
     
 0.750
KJW12032.1
Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.628
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
   
 
 0.589
Your Current Organism:
Lactobacillus spicheri
NCBI taxonomy Id: 216463
Other names: DSM 15429, JCM 15956, L. spicheri, LMG 21871, LMG:21871, LTH 5753, Lactobacillus spicheri Meroth et al. 2004
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