Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KJW11962.1Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)    
Predicted Functional Partners:
KJW11961.1
Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.924
KJW11963.1
CBS domain-containing protein ykuL; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.894
murI-2
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
  
  
 0.857
KJW13461.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.633
KJW11959.1
Hydrocarbon-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.602
KJW13178.1
With AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.546
KJW11693.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.507
KJW12119.1
Membrane protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
 
     0.496
Your Current Organism:
Lactobacillus spicheri
NCBI taxonomy Id: 216463
Other names: DSM 15429, JCM 15956, L. spicheri, LMG 21871, LMG:21871, LTH 5753, Lactobacillus spicheri Meroth et al. 2004
Server load: high (92%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.