Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KJW11963.1CBS domain-containing protein ykuL; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)    
Predicted Functional Partners:
murI-2
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
    
  0.931
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.897
KJW11962.1
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.894
KJW11961.1
Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.842
KJW11959.1
Hydrocarbon-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.751
KJW12482.1
Glycine/betaine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.693
KJW12583.1
Glycine/betaine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.693
KJW13079.1
Initiation-control protein; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
 
   0.661
KJW11763.1
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.659
KJW12051.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.500
Your Current Organism:
Lactobacillus spicheri
NCBI taxonomy Id: 216463
Other names: DSM 15429, JCM 15956, L. spicheri, LMG 21871, LMG:21871, LTH 5753, Lactobacillus spicheri Meroth et al. 2004
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