STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KJW11722.1Phosphocarrier protein HPr; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)    
Predicted Functional Partners:
KJW13462.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
KJW11723.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
KJW13031.1
PTS friuctose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.990
KJW13030.1
PTS mannose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.988
KJW13032.1
PTS mannose transporter subunit IID; Hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.951
KJW13166.1
PTS mannose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.950
hprK
Serine kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (g [...]
 
 
 
 0.945
KJW13015.1
Cellobiose-specific PTS system IIC component; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.940
KJW11967.1
Catabolite control protein A; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.939
KJW11607.1
PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.896
Your Current Organism:
Lactobacillus spicheri
NCBI taxonomy Id: 216463
Other names: DSM 15429, JCM 15956, L. spicheri, LMG 21871, LMG:21871, LTH 5753, Lactobacillus spicheri Meroth et al. 2004
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