Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KJW11727.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)    
Predicted Functional Partners:
KJW11955.1
Cell division protein FtsZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.723
mprF
Membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
       0.654
KJW11725.1
Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.652
KJW11724.1
1,2-diacylglycerol 3-glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.636
KJW11907.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.602
KJW13553.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.584
KJW11728.1
Glycerol phosphate lipoteichoic acid synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.581
KJW12056.1
Dithiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.580
KJW13515.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.576
KJW13918.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.557
Your Current Organism:
Lactobacillus spicheri
NCBI taxonomy Id: 216463
Other names: DSM 15429, JCM 15956, L. spicheri, LMG 21871, LMG:21871, LTH 5753, Lactobacillus spicheri Meroth et al. 2004
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