STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cwsAConserved hypothetical protein; Required for regulated cell division, cell wall synthesis and the maintenance of cell shape; Belongs to the CwsA family. (142 aa)    
Predicted Functional Partners:
wag31
Conserved secreted antigen Wag31; Function unknown but corresponds to antigen 84 of mycobacterium tuberculosis (Wag31) (see hermans et al., 1995). predicted to contain significant amount of coiled coil structure.
    
 
 0.965
crgA
Conserved hypothetical membrane protein; Involved in cell division; Belongs to the CrgA family.
    
 
 0.904
ppiA
Peptidyl-prolyl cis-trans isomerase A, PpiA; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
       0.757
fadE33
acyl-CoA dehydrogenase FadE33; Function unknown, but involved in lipid degradation.
      
 0.704
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
      
 0.698
fadE3
acyl-CoA dehydrogenase FadE3; Function unknown, but involved in lipid degradation.
      
 0.608
fadE22
acyl-CoA dehydrogenase FadE22; Function unknown, but involved in lipid metabolism.
      
 0.604
pbpA
Penicillin-binding protein PbpA; Involved in peptidoglycan synthesis (at the final stages). cell wall formation; PbpA is supposed to be responsible for the determination of the rod shape of the cell. its synthesizes cross-linked peptidoglycan from lipid intermediates.
      
 0.599
cyp123A3
Cytochrome P450s are a group of heme-thiolate monooxygenases. they oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
      
 0.598
pbpB
Penicillin-binding membrane protein PbpB; Involved in peptidoglycan biosynthesis.
      
 0.579
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.