STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ponA1Bifunctional penicillin-binding protein 1A/1B PonA1; Involved in peptidoglycan synthesis (at the final stages), cell wall formation. synthesis of cross-linked peptidoglycan from the lipid intermediates. the enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). (690 aa)    
Predicted Functional Partners:
wag31
Conserved secreted antigen Wag31; Function unknown but corresponds to antigen 84 of mycobacterium tuberculosis (Wag31) (see hermans et al., 1995). predicted to contain significant amount of coiled coil structure.
 
 
 
 0.936
MMAR_0070
Conserved hypothetical transmembrane protein.
  
    0.889
MMAR_0071
Transcriptional regulatory protein.
       0.874
dacB1
D-alanyl-D-alanine carboxypeptidase DacB1; Involved in peptidoglycan synthesis (at final stages). hydrolyzes the bound D-alanyl-D-alanine [catalytic activity: D-alanyl-D-alanine + H(2)O = 2 D- alanine].
      
 0.847
MMAR_1840
Penicillin-binding lipoprotein; Function unknown, possibly involved in cell wall biosynthesis.
 
 
 
 0.803
pbpB
Penicillin-binding membrane protein PbpB; Involved in peptidoglycan biosynthesis.
 
 
 
 0.796
rpsF
30S ribosomal protein S6 RpsF; Binds together with S18 to 16S ribosomal RNA.
 
     0.782
pbpA
Penicillin-binding protein PbpA; Involved in peptidoglycan synthesis (at the final stages). cell wall formation; PbpA is supposed to be responsible for the determination of the rod shape of the cell. its synthesizes cross-linked peptidoglycan from lipid intermediates.
 
 
 
0.772
ftsW
FtsW-like protein FtsW; Function unknown function in cell division; Belongs to the SEDS family.
 
 
 
 0.769
MMAR_1780
Conserved protein; Function unknown, possibly involved in cell division and chromosome partitioning.
   
 
 0.731
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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