STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMAR_0684Conserved hypothetical regulatory protein. (215 aa)    
Predicted Functional Partners:
trcR
Sensor part of the two-component regulatory system TrcS/TrcR. involved in transcriptional autoactivation: TrcR activates its own expression by interacting with the AT-rich sequence of the TrcR promoter.
   
  
 0.593
kdpE
Receiver domain of the two-component regulatory system Kdp/KdpE involved in the regulation of the Kdp operon.
   
  
 0.584
sirR
Transcriptional repressor SirR; Involved in transcriptional mechanism.
  
  
 0.574
embR
Transcriptional regulatory protein EmbR; Involved in transcriptional mechanism. thought to regulate the biosynthesis of the mycobacterial cell wall arabinan and resistance to ethambutol (Emb; dextro-2,2'- (ethylenediimino)-di-1-butanol), regulating EmbA and EmbB.
   
  
 0.573
MMAR_3156
Transcriptional regulatory protein (probably AraC/XylS-family); Involved in transcriptional mechanism.
   
  
 0.563
MMAR_4976
Conserved hypothetical transcriptional regulator (PadR-like family); Members of the PadR-like family are transcriptional regulators that appear to be related to the pfam01047 family. this family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.
   
  
 0.554
MMAR_5392
Transcriptional regulatory protein; Supposed involved in transcriptional mechanism.
   
    0.554
MMAR_1279
Causes DNA methylation.
   
    0.553
MMAR_1147
Transcriptional regulatory protein; Involved in transcriptional mechanism.
  
  
 0.543
MMAR_0653
Transcriptional regulatory protein (probably LysR-family); Possibly involved in transcriptional mechanism; Belongs to the LysR transcriptional regulatory family.
   
 
 0.537
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.