STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pks15/1Polyketide synthase Pks15/1; Catalyzes the elongation by iterative transfer of p- hydroxybenzoyl group from FadD22 (pHBA-S-FAdD22) to form p- hydroxyphenylalkanoate (pHPA) intermediates during phenolphthiocerol (PPOL) biosynthesis. PPOL is an important intermediate in the biosynthesis of phenolic glycolipid (mycosid B). Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (2104 aa)    
Predicted Functional Partners:
fas
Involved in lipid metabolism. fatty acid synthase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH.
  
0.999
MMAR_1180
N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide.
 
0.996
MMAR_3099
Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP).
 
0.995
MMAR_1250
Peptide synthetase Nrp (peptide synthase); Function unknown but contains 3 modules for the potential synthesis of a tripeptide.
 0.993
MMAR_3268
Non-ribosomal peptide synthetase; Involved in lipid metabolism. nine ext. modules, each module with predicted domain structure of C,a,T, domains ending in an integral te domain.
 
 
 0.990
MMAR_3098
Polyketide synthase PKS; A single module PKS, with the following domain structure when linked with U/S and D/S ORFs: (KS, ATProp, DH, ER, KR, ACP).
 
 
0.985
MMAR_3633
Peptide synthetase Nrp (peptide synthase); Function unknown but contains 3 modules for the potential synthesis of a tripeptide.
 0.983
MMAR_3176
Non-ribosomal peptide synthetase; Production of unknown peptide. contains 5 predicted modules of domain organiszation:Amt, CAMT, cat, cat, CAMT int te. the 'A' domain substrates have not been accurately predicted but probably Phe, Thr or ala).
 
 0.980
MMAR_3097
Non-ribosomal peptide synthetase; Nrp of 5 modules. domain structure (C, a, T) X 5, ending in a te domain. metabolite produced unknown.
 
 0.973
mbtB
Phenyloxazoline synthase MbtB; Involved in the biogenesis of the hydroxyphenyloxazoline-containing siderophore mycobactins. this peptide synthase forms amide bound between the carboxylic acid of salicylate and the alpha-amino group of serine (serine/threonine ligation).
 
 0.973
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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