STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMAR_1908Trehalose or maltose hydrolase; Function unknown but may be involved in trehalose biosynthesis. mycobacteria can produce trehalose from glucose 6-phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)-linked glucose polymers (the TreY-TreZ pathway) and from maltose (the TreS pathway). seems to have additional alpha-glucosidase activity. (904 aa)    
Predicted Functional Partners:
MMAR_1144
Hydrolase; Cellular metabolism.
  
 0.832
MMAR_1909
Conserved hypothetical protein.
       0.773
MMAR_3476
Conserved hypothetical protein.
  
    0.773
MMAR_1910
Hydrolase; Function unknown, probably involved in cellular metabolism.
       0.625
MMAR_1911
Conserved hypothetical secreted protein.
       0.550
otsB1
Trehalose-6-phosphate phosphatase OtsB1; Involved in trehalose biosynthesis (protective effect). mycobacteria can produce trehalose from glucose 6- phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)-linked glucose polymers (the TreY-TreZ pathway) and from maltose (the TreS pathway). seems to have additional alpha-glucosidase activity.
 
 
0.506
treZ
Maltooligosyltrehalose trehalohydrolase, TreZ; Involved in trehalose biosynthesis (protective effect). mycobacteria can produce trehalose from glucose 6- phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)-linked glucose polymers (the TreY-TreZ pathway) and from maltose (the TreS pathway).
 
  
 0.432
treS
Trehalose synthase TreS; Involved in trehalose biosynthesis (protective effect). converts maltose to trehalose. mycobacteria can produce trehalose from glucose 6-phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)- linked glucose polymers (the TreY-TreZ pathway) and from maltose (the TreS pathway).
 
  
 0.420
aglA
Alpha-glucosidase AglA; Involved in sugar metabolism (hydrolysis of terminal, non-reducing 1,4-linked d-glucose residues with release of d-glucose).
 
  
 0.402
pfkB_1
Phosphofructokinase, PfkB_1; Phosphofructokinase and related sugar kinases play an important role in the predominant pathway for fructose utilisation; Belongs to the carbohydrate kinase PfkB family.
  
  
 0.400
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.