STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aldSecreted L-alanine dehydrogenase Ald (40 kDa antigen); May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer [catalytic activity: L-alanine + H(2)O + NAD(+) = pyruvate + NH(3) + NADH]; Belongs to the AlaDH/PNT family. (371 aa)    
Predicted Functional Partners:
alr
Alanine racemase, Alr; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
 
 0.968
pntB
NAD(P) transhydrogenase (subunit beta) PntB; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
      0.909
aspC
Aspartate aminotransferase AspC; Involved in glutamate biosynthesis [catalytic activity: l-aspartate + 2-oxoglutarate = oxaloacetate + L- glutamate].
   
 
 0.908
MMAR_1929
Transcriptional regulatory protein (probably Lrp/AsnC-family); Involved in transcriptional mechanism.
     
 0.787
gltB
Ferredoxin-dependent glutamate synthase [NADPH] (large subunit) GltB; Probably involved in glutamate biosynthesis [catalytic activity: 2 L-glutamate + NADP(+) = L-glutamine + 2-oxoglutarate + NADPH].
      
 0.713
MMAR_1930
Conserved protein.
       0.524
nirA
Ferredoxin-dependent nitrite/sulphite reductase NirA; Generates nitrite from ammonia using oxidized ferredoxin [catalytic activity: ammonia + H(2)O + oh(-) + 3 oxidized ferredoxin = nitrite + 3 reduced ferredoxin]. the sulfite reductases catalyze the reduction of sulfite to sulfide, one step in the biosynthesis of sulfur- containing amino acids and cofactors.
      
 0.504
regX3
Transcriptional regulatory protein part of the two-component regulatory system RegX3/SenX3.
   
  
 0.496
gltA1
Citrate synthase I GltA1; Involved in tricarboxylic acid cycle (krebs cycle) [catalytic activity: citrate + CoA = acetyl-CoA + H2O + oxaloacetate]; Belongs to the citrate synthase family.
      
 0.481
glnA1
Glutamine synthetase GlnA1; Involved in glutamine biosynthesis [catalytic activity: ATP + L-glutamate + NH(3) = ADP + glutamine + orthophosphate].
     
 0.450
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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