Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
MMAR_1968Acetyltransferase; Function unknown, domain identity to ArgA, N- acetylglutamate synthase and related acetyltransferases suggests a role in amino acid transport and metabolism; Belongs to the acetyltransferase family. (174 aa)    
Predicted Functional Partners:
argJ
Glutamate N-acetyltransferase ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 
 0.965
argB
Acetylglutamate kinase ArgB; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
 
 0.957
MMAR_0743
Conserved hypothetical protein.
    
 0.907
aspC
Aspartate aminotransferase AspC; Involved in glutamate biosynthesis [catalytic activity: l-aspartate + 2-oxoglutarate = oxaloacetate + L- glutamate].
    
 0.905
gdh
NAD-dependent glutamate dehydrogenase Gdh; Catabolic GlutDH involved in the utilization of glutamate and other amino acids of the glutamate family. generates 2-oxoglutarate from L-glutamate [catalytic activity: L-glutamate + H(2)O + NAD(+) = 2-oxoglutarate + NH(3) + NADH].
     
  0.900
pgsA3
PGP synthase PgsA3; Involved in acidic phospholipid biosynthesis. this protein probably catalyzes the committed step to the synthesis of the acidic phospholipids [catalytic activity: CDP-diacylglycerol + glycerol-3-phosphate = CMP + 3-(3- phosphatidyl)-glycerol 1-phosphate]; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.663
argG
Argininosuccinate synthase ArgG; Arginine biosynthesis [catalytic activity : ATP + l- citrulline + l-aspartate = AMP + diphosphate + l- argininosuccinate]; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.656
MMAR_0970
Conserved protein; Belongs to the UPF0336 family.
 
     0.598
gltB
Ferredoxin-dependent glutamate synthase [NADPH] (large subunit) GltB; Probably involved in glutamate biosynthesis [catalytic activity: 2 L-glutamate + NADP(+) = L-glutamine + 2-oxoglutarate + NADPH].
     
 0.571
argR
Arginine repressor ArgR; Regulates arginine biosynthesis genes.
  
  
 0.569
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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