Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMAR_1983Conserved hypothetical membrane protein. (299 aa)    
Predicted Functional Partners:
treZ
Maltooligosyltrehalose trehalohydrolase, TreZ; Involved in trehalose biosynthesis (protective effect). mycobacteria can produce trehalose from glucose 6- phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)-linked glucose polymers (the TreY-TreZ pathway) and from maltose (the TreS pathway).
  
 0.692
glgB
1,4-alpha-glucan branching enzyme GlgB; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
 0.690
MMAR_4504
Function unknown, possible membrane protein involved in the export of O-antigen and teichoic acid.
 
  
 0.599
MMAR_4503
Conserved hypothetical membrane protein; Function unknown, possibly involved in lipopolysaccharide synthesis.
  
  
 0.567
eccB5
Conserved membrane protein; An ATPase (By similarity). Part of the ESX-5 specialized secretion system, which is responsible for the secretion of EsxN and a number of PE_PGRS and PPE proteins.
 
    0.554
MMAR_2568
Carbohydrate phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.538
glgP
Glycogen phosphorylase GlgP; Catalytic activity : {(1,4)-alpha-D-glucosyl}(N) + phosphate = {(1,4)-alpha-D-glucosyl}(N-1) + alpha-D- glucose 1-phosphate.
  
 
 0.538
MMAR_1116
Conserved hypothetical transmembrane protein.
  
     0.523
MMAR_5366
Conserved secreted protein.
  
  
 0.472
manB
d-alpha-D-mannose-1-phosphate guanylyltransferase ManB; Involved in GDP-mannose biosynthesis and biosynthesis of nucleotide-activated glycero-manno-heptose (D-alpha-D pathway): generates GDP-mannose and phosphate from GTP and alpha-D-mannose 1-phosphate. ManB product is needed for all mannosyl glycolipids and polysaccharides which, like rhamnosyl residues, are an important part of the mycobacterium envelope [catalytic activity: alpha-D- mannose 1-phosphate + GTP = GDP-mannose + phosphate].
 
 
 0.463
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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