Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMAR_1995Conserved hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands. (161 aa)    
Predicted Functional Partners:
MMAR_1993
Conserved hypothetical membrane protein; In M. tuberculosis H37Rv thought to be regulated by LexA.
     
 0.745
nrdR
Membrane-associated regulatory protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.742
MMAR_2358
Conserved hypothetical protein; Function unknown. partial Cdd COG0030, KsgA, dimethyladenosine transferase (rRNA methylation) [translation, ribosomal structure and biogenesis].
  
  
 0.548
ksgA
Dimethyladenosine transferase KsgA; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.548
MMAR_5099
PE-PGRS family protein.
 
     0.474
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
       0.466
MMAR_1172
Dehydrogenase; Function unknown, probably involved in cellular metabolism.
  
     0.425
MMAR_1339
Conserved hypothetical protein.
     
 0.401
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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