Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMAR_1998Conserved protein. (325 aa)    
Predicted Functional Partners:
MMAR_1997
Conserved hypothetical hydrolase; Function unknown, probably involved in cellular metabolism.
       0.785
MMAR_1996
Conserved hypothetical protein; Function unknown but contains identity to an epimerase involved in phenazine biosynthesis.
       0.733
MMAR_1999
Conserved hypothetical secreted protein; Function unknown but contains weak similarity to V8- like Glu-specific endopeptidases involved in amino acid transport and metabolism.
       0.707
whiB2
Transcriptional regulatory protein Whib-like WhiB2; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.559
metH
5-methyltetrahydrofolate--homocysteine methyltransferase, MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.557
whiB1
Transcriptional regulatory protein Whib-like WhiB1; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.539
whiB
Transcriptional regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.524
MMAR_2261
Unidentified antibiotic-transport integral membrane ABC transporter; Thought to be involved in active transport of antibiotic across the membrane (export): unidentified antibiotic resistance by an export mechanism. responsible for the translocation of the substrate across the membrane.
  
     0.495
MMAR_3493
Conserved hypothetical protein.
  
    0.488
nucS
Conserved hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.485
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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