Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MMAR_2020Conserved hypothetical protein. (127 aa)    
Predicted Functional Partners:
MMAR_2021
Conserved integral membrane alanine and leucine rich protein.
       0.813
MMAR_2024
Conserved integral membrane alanine, valine and leucine rich protein; Function unknown but domain identity suggests a role in amino acid transport.
 
     0.743
ceoC
TRK system potassium uptake protein CeoC; Part of a potassium transport system.
 
    0.721
ceoB
TRK system potassium uptake protein CeoB; Part of a potassium transport system.
 
    0.721
ceoC1
TRK system potassium uptake protein CeoC1; Part of a potassium transport system.
 
    0.712
MMAR_2019
Conserved hypothetical protein.
       0.607
topA
DNA topoisomerase I TopA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA [...]
  
  
 0.574
MMAR_1971
Conserved 35 kDa alanine rich protein; Function unknown but domain identity to COG1842, PspA, phage shock protein a (IM30), suppresses sigma54- dependent transcription.
  
  
 0.556
hspX
Peptidase heat shock protein X, HspX; Possibly involved in adaptation. hydrolizes specific peptides and/or proteins; Belongs to the peptidase M48B family.
   
  
 0.544
polA
DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.522
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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