Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MMAR_2288Membrane protein. (335 aa)    
Predicted Functional Partners:
MMAR_2287
Conserved protein.
 
  
 0.987
moxR1
Transcriptional regulatory protein, MoxR1; Involved in transcriptional mechanism.
 
  
 0.956
fabG1
3-oxoacyl-[acyl-carrier protein] reductase, FabG1; Involved in the fatty acid biosynthesis pathway (first reduction step) (mycolic acid biosynthesis); reduces KasA/KasB products [catalytic activity: (3R)-3- hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl- [acyl-carrier protein] + NADPH].
       0.731
hemZ
Ferrochelatase HemZ; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.696
iipB
Mycobacterial invasion and intracellular persistence protein, IipB; Homology to cell wall-associated hydrolases. possibly an exported protein of the NLP/P60 family.
     
 0.678
inhA
Enoyl-[acyl-carrier-protein] reductase, InhA; Involved in mycolic acid biosynthesis. second reductive step in fatty acid biosynthesis [catalytic activity: acyl-[acyl-carrier protein] + NAD(+) = TRANS-2,3- dehydroacyl-[acyl-carrier protein] + NADH].
       0.670
MMAR_1883
Magnesium chelatase; Function unknown, possibly introduces a magnesium ion into specific substrate/compound.
  
 
 0.628
MMAR_4541
Chelation, introducing a magnesium ion into specific substrate.
  
 
 0.628
MMAR_5296
Conserved protein.
  
     0.600
MMAR_1700
Conserved hypothetical protein.
 
     0.559
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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